On October 10th, the Jubilee Symposium IOC 125 years has reached its third act, continuing the anniversary celebrations of the Oswaldo Cruz Institute (IOC/Fiocruz).
The program began with the inauguration of the Institute's first high biological containment level 3 (NBA3) environment, followed by the 9th Research and Innovation Symposium, which featured five thematic sessions on biosafety, its challenges and scientific advances.
During the opening ceremony, held at the Carlos Chagas Pavilion, the director of IOC, Tania Araujo-Jorge, highlighted the importance of the new structure and the role of partnerships that made its construction possible. She noted that the project received a parliamentary amendment from Congressman Paulo Ramos and the support of the president of the Federaliocruz and collaboration of the company Biotec, responsible for the construction and maintenance of the module.
Click here to read the article on the topic.
Afterwards, the activities were directed to the Emmanuel Dias auditorium, with the opening of the 9th Research and Innovation Symposium of IOCLuciana Garzoni, Director of Research, Technological Development, and Innovation, gave a brief overview of the biomodule's implementation history and thanked the team that made the project possible.
“This laboratory is part of a structuring and strategic action of extreme importance for the future of research and for confronting health emergencies,” he emphasized.
Vice President of Research and Biological Collections at Fiocruz, Alda Maria Cruz, pointed out that the Covid-19 pandemic left important legacies and boosted scientific advances.
“Biomodel studies are fundamental to public health; they are a kind of master key to discoveries,” he emphasized.
The coordinator of the Internal Biosafety Committee of IOC, Dalziza Victalina, addressed the Institute’s commitment to public service.
“We are not just here to celebrate science, but also to commit to social responsibility,” he emphasized.
Scientific sessions
In the first lecture, entitled 'Laboratory Animal Science: The Concept of High Containment for Biological and Animal Experimentation', the coordinator of the NB3 Platform of IOC, Marco Horta, explained the concepts and infrastructure needed to implement high biological and animal containment environments.
He highlighted the differences between NB3 and NBA3 laboratories and described essential elements of this type of facility—such as double-door rooms, automated handwashing systems, personal protective equipment, air containment and filtration, continuous monitoring and alarms, and the importance of regular training and staff competency assessments.
'The importance of the Experimentation Center IOC in research into solutions for health emergencies in Brazil' was the theme of the presentation by the head of the Institute's Laboratory for Technological Development in Virology, Marcelo Alves Pinto.
The expert discussed the importance of the Institute's experimental center in addressing health emergencies in Brazil. He noted that more than 90% of countries lack similar infrastructure, making the investment in NBA3 even more strategic.
The afternoon's program began with the coordinator of the Animal Experimentation Center (CEA/IOC), André Nunes de Sales, who presented the 'Panorama of laboratory animal science in IOC'.
He detailed the capacity and infrastructure of CEA's laboratories, presented data on the number of researchers and ongoing projects, and showed a video showing details of the infrastructure of a high-containment laboratory.
Next, the director of IOC discussed 'Translational Research: A Case Study from Concept to Clinical Practice.' She explained that translational research, a concept consolidated since the 1990s, seeks to integrate different stages.
According to her, the "translational spectrum" consists of five phases: basic discoveries; translation to humans; translation to patients; translation to clinical practice; and translation to the community. She exemplified the theory with the project using selenium in patients with Chagas disease, presenting partial results and highlighting the complexity of the path to practical application of the studies.
Closing the program, four institutional technologies that strengthen research and innovation capacity were presented.
A postdoctoral student in the Postgraduate Program in Cellular and Molecular Biology at IOCLaura Lacerda Coelho presented the Incucyte Platform, a device that will soon be incorporated into the Institute. The researcher demonstrated the technology's potential for real-time monitoring of cell cultures, highlighting the gains in precision and agility for experiments that require continuous observation.
Next, researcher Vinicius de Frias Carvalho presented the Micro-CT (Computed Tomography) Platform for small animals, a technology that has been in operation for about a year. He explained the capabilities offered by the equipment and demonstrated how the associated software enables detailed analysis of internal structures.
Pedro Paulo Manso presented the Confocal Microscopy Platform, which has just incorporated the LSM 980 equipment, expanding its application possibilities. Created in 1995, the platform currently has 95 active users and enables super-resolution, 3D, and 4D imaging.
Finally, Monique Ribeiro, a veterinarian at CEA and head of one of the Institute's animal facilities and the Bioimaging Platform, presented the Lago X system. The equipment provides high-resolution images, uses free and intuitive software, and is compatible with other imaging systems—a feature that facilitates the continuation of research already initiated on other platforms. Ribeiro also highlighted that the system reduces the number of animals used in experiments and eliminates invasive procedures, as it allows for monitoring the same animals over time.
On October 10th, the Jubilee Symposium IOC 125 years has reached its third act, continuing the anniversary celebrations of the Oswaldo Cruz Institute (IOC/Fiocruz).
The program began with the inauguration of the Institute's first high biological containment level 3 (NBA3) environment, followed by the 9th Research and Innovation Symposium, which featured five thematic sessions on biosafety, its challenges and scientific advances.
During the opening ceremony, held at the Carlos Chagas Pavilion, the director of IOC, Tania Araujo-Jorge, highlighted the importance of the new structure and the role of partnerships that made its construction possible. She noted that the project received a parliamentary amendment from Congressman Paulo Ramos and the support of the president of the Federaliocruz and collaboration of the company Biotec, responsible for the construction and maintenance of the module.
Click here to read the article on the topic.
Afterwards, the activities were directed to the Emmanuel Dias auditorium, with the opening of the 9th Research and Innovation Symposium of IOCLuciana Garzoni, Director of Research, Technological Development, and Innovation, gave a brief overview of the biomodule's implementation history and thanked the team that made the project possible.
“This laboratory is part of a structuring and strategic action of extreme importance for the future of research and for confronting health emergencies,” he emphasized.
Vice President of Research and Biological Collections at Fiocruz, Alda Maria Cruz, pointed out that the Covid-19 pandemic left important legacies and boosted scientific advances.
“Biomodel studies are fundamental to public health; they are a kind of master key to discoveries,” he emphasized.
The coordinator of the Internal Biosafety Committee of IOC, Dalziza Victalina, addressed the Institute’s commitment to public service.
“We are not just here to celebrate science, but also to commit to social responsibility,” he emphasized.
Scientific sessions
In the first lecture, entitled 'Laboratory Animal Science: The Concept of High Containment for Biological and Animal Experimentation', the coordinator of the NB3 Platform of IOC, Marco Horta, explained the concepts and infrastructure needed to implement high biological and animal containment environments.
He highlighted the differences between NB3 and NBA3 laboratories and described essential elements of this type of facility—such as double-door rooms, automated handwashing systems, personal protective equipment, air containment and filtration, continuous monitoring and alarms, and the importance of regular training and staff competency assessments.
'The importance of the Experimentation Center IOC in research into solutions for health emergencies in Brazil' was the theme of the presentation by the head of the Institute's Laboratory for Technological Development in Virology, Marcelo Alves Pinto.
The expert discussed the importance of the Institute's experimental center in addressing health emergencies in Brazil. He noted that more than 90% of countries lack similar infrastructure, making the investment in NBA3 even more strategic.
The afternoon's program began with the coordinator of the Animal Experimentation Center (CEA/IOC), André Nunes de Sales, who presented the 'Panorama of laboratory animal science in IOC'.
He detailed the capacity and infrastructure of CEA's laboratories, presented data on the number of researchers and ongoing projects, and showed a video showing details of the infrastructure of a high-containment laboratory.
Next, the director of IOC discussed 'Translational Research: A Case Study from Concept to Clinical Practice.' She explained that translational research, a concept consolidated since the 1990s, seeks to integrate different stages.
According to her, the "translational spectrum" consists of five phases: basic discoveries; translation to humans; translation to patients; translation to clinical practice; and translation to the community. She exemplified the theory with the project using selenium in patients with Chagas disease, presenting partial results and highlighting the complexity of the path to practical application of the studies.
Closing the program, four institutional technologies that strengthen research and innovation capacity were presented.
A postdoctoral student in the Postgraduate Program in Cellular and Molecular Biology at IOCLaura Lacerda Coelho presented the Incucyte Platform, a device that will soon be incorporated into the Institute. The researcher demonstrated the technology's potential for real-time monitoring of cell cultures, highlighting the gains in precision and agility for experiments that require continuous observation.
Next, researcher Vinicius de Frias Carvalho presented the Micro-CT (Computed Tomography) Platform for small animals, a technology that has been in operation for about a year. He explained the capabilities offered by the equipment and demonstrated how the associated software enables detailed analysis of internal structures.
Pedro Paulo Manso presented the Confocal Microscopy Platform, which has just incorporated the LSM 980 equipment, expanding its application possibilities. Created in 1995, the platform currently has 95 active users and enables super-resolution, 3D, and 4D imaging.
Finally, Monique Ribeiro, a veterinarian at CEA and head of one of the Institute's animal facilities and the Bioimaging Platform, presented the Lago X system. The equipment provides high-resolution images, uses free and intuitive software, and is compatible with other imaging systems—a feature that facilitates the continuation of research already initiated on other platforms. Ribeiro also highlighted that the system reduces the number of animals used in experiments and eliminates invasive procedures, as it allows for monitoring the same animals over time.
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