The Vice-Director of Research, Technological Development and Innovation of Instituto Oswaldo Cruz (IOC/Fiocruz), through the Technological Innovation Center (NIT), linked to Research and Innovation Support Platform (PAPI), seeks to subsidize the implementation of partnerships to generate innovative products and processes based on projects under development at the Institute around the new coronavirus.
Of strategic importance, the 'Technological Showcase in Covid-19 of Instituto Oswaldo Cruz' gives visibility to innovations that contribute to responses to the public health emergency caused by the SARS-CoV-2 pandemic.
Created in 2014, the Research and Innovation Support Platform of the IOC has expertise in managing Research, Development and Innovation activities, seeking excellence in the management of the Institute's projects. Through the NIT, it also seeks to contribute to the expansion of the impact of the research developed in the IOC through the development of partnerships and actions that stimulate innovation for the benefit of the quality of life of the Brazilian population.
The Technological Showcase IOC is the result of the maturing of ideas to foster innovation in the IOC and counted on the union of several institutional bodies, such as the Board of Directors, the Research Vice-Director, the Research and Innovation Support Platform, the Technological Innovation Nucleus, the Journalism and Communication Service and the Information Technology Department.
Discover below the technologies in Covid-19 being developed by the scientific and academic community of the Instituto Oswaldo Cruz.
For partnerships, guidance, questions or more information, contact NIT-IOC by email nit @ioc.fiocruz.br.
New Drugs
Evaluation of the susceptibility of animal models to SARS-CoV-2 infection in order to prove the efficacy and safety of new substances with promising antiviral activity
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New Drugs
Seeking new potent inhibitors of SARS-CoV-2 enzymes through deep learning, molecular modeling and in vitro studies
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New Drugs
Naphthoquinone derivatives acting on SARS-CoV-2 proteases
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New Drugs
Development of DNA vaccines against SARS-CoV2: Analysis of immune responses and protection
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New Drugs
Study of the replicative cycle and evaluation of the modulatory effect of different molecules on the morphology and morphogenesis of SARS-CoV-2 in different cell lines
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New Drugs
Investigating molecular mechanisms of pulmonary fibrosis in Covid-19
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New Drugs
In vitro model for studying the invasiveness of SARS-CoV-2 in the blood-brain and placental barrier and testing of antiviral drugs
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New Drugs
Proposition of new molecules that modulate SARS-CoV-2 replication: screening and virtual structural optimization, synthesis, in vitro antiviral evaluation, pharmaceutical formulation and pharmacokinetic studies
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New Drugs
Vasculopathy and severity in experimental Covid-19 and the role of ACE2
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New Drugs
Control of the inflammatory response and replication of SARS-CoV-2 by VIP and PACAP neuropeptides
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Diagnosis
Development of a diagnostic method for detection of the SARS-CoV-2 viral particle using alternative antibodies
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Diagnosis
Development of a more cost-effective real-time PCR assay for the molecular diagnosis of Covid-19
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Diagnosis
Rapid detection of SARS-Cov-2 RNA in nasopharyngeal and oropharyngeal secretions
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Diagnosis
Analytical diagnosis in individuals affected by Covid-19
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Diagnosis
Diagnosis of SARS-CoV-2 infection: inclusive testing of individuals with inborn errors in the immune system
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Diagnosis
Implementation of anti-SARS-CoV-2 neutralizing antibody quantification technology by pseudovirus-based assay
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Diagnosis
Immunity, inflammation and coagulation in Covid-19: search for disease resistance markers through multiparametric analyzes in the ambition to build a vaccine strategy
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Diagnosis
Point-of-Care Rapid Molecular Diagnostic Kit for Covid-19
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Contagion Prevention and Reduction
Evaluation of the susceptibility of animal models to SARS-CoV-2 infection aiming at the development of a vaccine prototype
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Contagion Prevention and Reduction
Recombinant BCG expressing secreted antigens for the development of new vaccines against Covid-19
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Contagion Prevention and Reduction
Multifactorial in vitro study of a new potential immunomodulatory tool to combat Covid-19: The BCG vaccine
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Contagion Prevention and Reduction
Mapping of linear antibody epitopes in Covid-19 infection
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Contagion Prevention and Reduction
Recombinant mycobacteria for the expression of SARS-CoV-2 antigens in the secreted form
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Health Information and Communication
Expresso Covid-19 & Community Health: a differential for vulnerable communities
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Health Information and Communication
CHA platform for educators: Knowledge, Skills and Attitudes in health to face social and educational changes in the pandemic and post-pandemic period of Covid-19
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