Promovida bienalmente pela Sociedade Internacional de Aids (IAS, nas sigla em inglês), a Conferência Mundial de Aids 2008 reuniu especialistas de todo o mundo na Cidade do México, de 3 a 8 de agosto, para discutir os principais avanços e desafios no enfrentamento da epidemia. Pesquisadores do Instituto Oswaldo Cruz (IOC/Fiocruz) integraram o evento em mesas-redondas e apresentações orais. Confira a cobertura completa no site do evento.

Os pesquisadores do IOC participaram com as seguintes atividades:

Segunda-feira (dia 04)
The Toll-like receptor 2 ligand Zymosan inhibits HIV-1 replication in human primary cells
H.K. Pimenta-Inada, L.G. Jucá, C.C. Cirne-Santos, D.C. Bou-Habib

Trypanosomatid replication in HIVinfected macrophages
D. Chequer Bou-Habib

Interleukin 27 (IL-27) inhibits HIV-1 replication in primary human cells independently of beta-chemokine production
L. Gobbo Jucá, H. Kimie Pimenta-Inada, C.Cesar Cirne-Santos, D. Chequer Bou-Habib

Trends of integrase inhibitors drug resistance in treatment-naive patients with HIV-1 subtype C infection in Brazil
C. Passaes, M. Guimarães, S. Almeida, M.Morgado

Temporal trends and evolutionary history of HIV-1 CRF31_BC in Porto Alegre, Brazil from 1998 to 2006
M. Guimarães, C. Passaes, G. Bello, R.Lorete, S. Almeida, R. Medeiros, P.R.Alencastro, M. Morgado

Evaluation of the impact of HIV-1 genetic diversity subtypes in the antiretroviral therapy efficacy in infected patients in Rio de Janeiro, Brazil: a follow up study
S. Chequer Fernandez, C. Santos Rodrigues, D. Rufino dos Santos, J.H. Pilotto, M. Morgado

Terça-feira (dia 05)
Low emergence of drug resistance after HAART interruption at delivery in a cohort of HIV+ pregnant Women in Rio de Janeiro, Brazil
J.H. Pilotto, B. Grinsztejn, V.G. Veloso,J.-C. Couto-Fernandez, A. Rodrigues-Pedro, J.E. Ribeiro, E. Lima, R. Khalili, S. Muri, R.Ismerio, J. Currier, M.G. Morgado

The compound 6-chloro-1,4-dihydro-4-oxo-1-(&946;-D-ribofuranosyl) quinoline-3-carboxylic acid inhibits HIV-1 replication by targeting the enzyme reverse transcriptase
D. Rodrigues, T. Souza, C. Cirne-Santos,C.F. Fontes, V. Ferreira, I. Marquez, M.C. DeSouza, D. Bou-Habib

Quarta-feira (dia 06)
Preclinical development / Preclinical Development and Animal Models for HIV Vaccines
M. Morgado

Evaluation of the ViroSeq HIV-1 genotyping system performance in prevalent non-B and recombinant HIV-1 samples from patients failing antiretroviral therapy in Rio de Janeiro
J.C. Couto-Fernandez, C. Silva de Jesus, M.Morgado

Quinta-feira (dia 07)
Evidence of multiple HIV-1 subtype C introductions in Southeast Brazilian region
G. Bello, M. Guimarães, J.C. Couto-Fernandez, C. Passaes, J. Casseb, S.Almeida, R. Alcade, M. Morgado

HIV-1 replication is enhancend by the macrophage migration inhibitory factor
E. Regis, V. Barreto-de-Souza Brasil Silva,L. Leng, R. Bucala, M. Bozza, D.C. Bou-Habib

The neurotrophins NGF, BDNF and proNGF induce enhancement of HIV-1 replication in primary human macrophages
T. Souza, D. Rodrigues, E. Araujo, C. Fontes,D. Bou-Habib

09/08/08

.